Serum Herpes Simplex Virus

Serum Herpes Simplex Antibodies Test

The serum herpes simplex antibodies test detects antibodies to the herpes simplex virus (HSV), which includes HSV-1 and HSV-2. While HSV-2 is more commonly linked to genital herpes, while HSV-1 is primarily associated with oral herpes (cold sores).

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Procedure for the test

This test involves taking a sample of blood, which is then analysed in a laboratory to identify the presence and levels of antibodies to HSV.

Before the test

No specific preparation is required for this test. However, it is advised that you are well-hydrated before the test.

During the test

Our healthcare professional will insert a needle to draw blood. While some individuals may feel minor pain or a stinging feeling, others experience only slight discomfort. After the procedure, you may notice mild throbbing or a small bruise at the puncture site.

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Purpose of the test

The test is used to determine if an individual has been previously infected with HSV-1 or HSV-2. It measures antibodies, which are produced by the immune system in response to the virus. It is important to note that this test identifies not the virus but the antibodies.

Understanding the results

Abnormal results:

When a result is positive, it suggests a prior or recent infection with HSV. Additional tests may be needed to confirm a recent infection. Statistics show that approximately 20–50% have antibodies for HSV-2, while 70% of adults have been exposed to HSV-1.

HSV remains in the body for life, potentially lying dormant and causing no issues, or it may reactivate periodically. This test does not indicate whether the virus is active.

Normal Results:

A negative result usually indicates no prior infection with Herpes simplex virus 2 or herpes simplex virus 1. However, the test may produce a false-negative result if the exposure occurred recently (within the past few weeks to three months). This is because the body takes time to produce detectable levels of antibodies.

Things to consider

Even without visible symptoms, it is possible to transmit HSV through sexual or close physical contact. To reduce the risk of transmission:

  • Do not share personal items such as towels, toothbrushes, or lipstick. Ensure dishes and utensils are thoroughly washed before others use them.
  • Avoid vaginal, anal, or oral sex when sores are present near the mouth, genitals, or anus.
  • Wash your hands thoroughly with soap and water after touching sores.
  • Refrain from kissing or oral contact when cold sores are visible.

Potential risk factors

The risks associated with blood collection are minimal but may include:

  • Rarely, infection at the puncture site
  • excessive bleeding
  • Bruising or haematoma
  • Feeling faint or lightheaded

Inform your partner about your HSV status before engaging in sexual activity. If both agree to proceed, use latex or polyurethane condoms for protection.

Schedule an appointment

If you are concerned about HSV or would like to schedule an HSV test, contact us at the Health Screening Clinic to book an appointment today!

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