Metabolic · Health Screening

Weight ManagementScreening

Metabolic profiling to understand factors influencing weight including hormones and metabolism.

Understanding Weight Management

When weight refuses to respond to genuine effort, the right question is not "what is wrong with my willpower?" but "what is my biology doing?" A meaningful minority of stubborn weight problems have measurable physiological contributors: an underactive thyroid slowing metabolic rate, insulin resistance locking the body into fat storage, PCOS in women, cortisol excess, and medication effects among them.

Insulin resistance deserves particular attention because it is so common and so self-reinforcing: excess visceral fat drives resistance, resistance raises insulin, and high insulin promotes further fat storage while blocking fat release — a loop that makes conventional dieting feel like swimming upstream. It shows in blood as rising HbA1c, high triglycerides with low HDL, and often raised liver enzymes (the fatty liver signature), all years before diabetes develops.

Testing changes the conversation. Finding hypothyroidism means treatment that restores metabolic rate; finding insulin resistance means strategies that specifically work for it (resistance training, protein-forward eating, sleep); finding PCOS opens well-established management routes; and finding nothing abnormal is liberating too — it confirms energy balance is the lever, and rules out the nagging "what if" that undermines motivation.

Risk Indicators

  • Difficulty losing weight
  • Slow metabolism
  • Hormonal weight gain
  • Appetite changes
Luciana

Expert Care by Luciana

Our experienced registered nurse performs gentle blood draws with complete discretion. Your results are explained in a clear written report.

Diagnostic Path

Identifying clinical markers associated with weight management requires a high-resolution laboratory profile. Below are the recommended diagnostic assessments specifically calibrated for this concern.

Our Full Body MOT packages measure the weight-relevant biology comprehensively: thyroid function (TSH, Free T4), HbA1c and glucose, full lipid profile, liver enzymes, uric acid, plus BMI and blood pressure recorded by our nurse. For women with PCOS features, the Female Hormonal Health Screening adds the androgen and LH:FSH picture. Re-testing after six months of change shows the internal improvements — often visible in blood before the scales fully reflect them.

When to See Your GP Urgently

Screening is for people without acute symptoms. If any of the following apply, please seek medical care first:

  • Rapid unexplained weight gain with facial rounding and easy bruising — see your GP
  • Weight gain with severe fatigue, cold intolerance and constipation — see your GP
  • Unexplained weight LOSS — always see your GP
  • Breathlessness or swelling with weight gain — see your GP promptly

Frequently Asked Questions

Could my thyroid be why I cannot lose weight?

It is worth checking — hypothyroidism slows metabolism and affects around 2% of the population, with subclinical forms far more common, especially in women. That said, thyroid problems typically account for modest weight change; testing settles the question either way, which is precisely the point.

What blood results suggest insulin resistance?

The classic cluster: HbA1c creeping into the 40s (mmol/mol), triglycerides above 1.7 with HDL below 1.0–1.3, raised ALT/GGT and rising uric acid, often with increased waist circumference. Your report will explicitly flag this pattern if present, with practical guidance.

Why do I gain weight around my middle specifically?

Visceral (abdominal) fat is hormonally driven — insulin, cortisol and sex-hormone changes (including menopause) all favour central storage. It is also the metabolically active fat that drives health risk, which makes it both the problem and the priority.

What if all my results are normal?

Then you have valuable clarity: no hidden brake, and energy balance strategies will work. Many patients find this genuinely motivating — and the baseline lets you verify improving metabolic health as you go, whatever the scales say week to week.

Related Reading

Recommended Tests

Advanced Full Body MOT

View DetailsGBP449

Platinum Full Body MOT – Men

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Platinum Full Body MOT – Women

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You will receive a detailed written report from our registered nurse with all examination findings and lab results.

Not sure which test you need? We'll guide you.

Book a health screening without choosing a package — our registered nurse will call you before your visit to talk through your health goals and recommend the right tests for you. No obligation, and you only pay in clinic for what you choose.

Guided bookings open from two days ahead so our team can call you first. Outside clinic hours? Message us on WhatsApp and we’ll reply as soon as we open.

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Clinical Testimonials.

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Clinical Leadership

Meet Your Experts.

NMC Registered Nurse
Luciana F. F. Cirillo
Lead Clinical Nurse

Luciana F. F. Cirillo

Registered Nurse (NMC)

Our Lead Clinical Nurse, experienced in gentle phlebotomy and comprehensive written reports for every patient.

NMC Registered Nurse
Precious Agbonmamwen
Registered Adult Nurse

Precious Agbonmamwen

Registered Nurse (NMC) · BSc Biomedical Science

A Registered Adult Nurse with a background in Biomedical Science, experienced in surgical nursing, pre-assessment and patient care. Precious is passionate about safe, compassionate, patient-centred care — and brings the calm, organised touch of a former BRIT Awards and royal-events manager to every appointment.

NMC PIN: 20H1641E
Clinical Governance

Our clinic operates in line with UK regulatory standards, with fully registered healthcare professionals providing safe, compliant, and high-quality care. Patients should expect nothing less.

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Find Us in London

Our Address

20 Old Brompton Road
South Kensington
London SW7 3DL

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Call Us

020 7183 3570

Open 7 Days a Week

Mon–Thu: 9am–6pm · Fri: 8am–5pm
Sat–Sun: 10am–4pm

How to Get Here

CircleDistrictPiccadilly

South Kensington Station

2 minute walk

Bus: 14, 74, 414, C1

Registered & Regulated Care

Your blood tests are performed by experienced, fully registered nurses and clinically overseen by a GMC-registered GP. We are regulated in the UK and committed to the highest standards of clinical excellence.

Dr Mehdi Fard

Dr Mehdi Fard

GMC: 6070368

MD, MRCGP, CPFC, CPSO (Canada), GMC, MCC

Luciana F. F. Cirillo

Luciana F. F. Cirillo

Registered Nurse

NMC: 25C1591E

Precious Agbonmamwen

Precious Agbonmamwen

Registered Adult Nurse

NMC: 20H1641E · BSc Biomedical Science

CQC Registered · 1-20629579981General Medical CouncilNursing & Midwifery Council